Barely Significant
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Targeting ST3GAL1 to downregulate ligands for the glycoimmune checkpoint Siglec-7 and reverse immune escape in hepatocellular carcinoma.

Cancer Immunol Immunother · 2026 · PMC13069034 · PMID 41961075

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6 ), although there is a trend for better overall survival but it did not reach statistical significance.

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highly significantno p-value reported
When ST3GAL1 was silenced in the Huh7 sorafenib-resistant cells, cetuximab induced a highly significant increases in the percentages of CD107a (Fig. 5 b) and IFN-g (Fig. 5 c) on PBNKS, as compared to pVoid transfected Huh7 sorafenib-resistant cells.

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