Cell-SELEX identifies a DNA aptamer for highly selective in vivo siRNA delivery in cholangiocarcinoma.

A similar assay was then performed in which aptamer-stained cells were scraped from wells and aptamer binding was measured by qPCR; this more sensitive approach identified significant binding of Aptamers 1, 4, 8, and 9 with nearly significant binding of Aptamer 6 ( Fig. 2 C).

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