Similar Changes in Proviral Landscapes Over 10 Years in 40 Individuals With Diverging HIV Reservoir Dynamics and Viral Load Kinetics.

Meanwhile, while the numbers of defective HIV DNA (3′ deletions/hypermutations and 5′ deletions) detected with the IPDA showed a trend of a decrease over time in the 2 groups with total HIV DNA decrease, they remained stable or even increased in the 2 groups with an increase in total HIV DNA ( Figure 2 B ).

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