Comprehensive overview of the global pharmacogenetic and functional variability in NUDT15.

Hum Genomics · 2026 · PMC13069803 · PMID 41935317

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

a clear trendno p-value reported

Notably, we observed a clear trend towards increased risk and likelihood for dose reduction among NUDT15*5 carriers with individual odds ratios (OR) for allele carriers ranging from 2.7 to 13.1 and three studies individually reaching statistical significance (p < 0.05).

also in 19,460 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.