Association between insulin resistance trajectories and perinatal complications: a retrospective cohort study.

Front Endocrinol (Lausanne) · 2026 · PMC13070787 · PMID 41982770

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did not reach statistical significanceno p-value reported

For GDM, a moderately increased association was observed in H2 (aRR, 1.61 [95% CI, 1.19–2.61]; P<0.01), while H3 demonstrated a higher relative risk in the unadjusted model (aRR, 2.00 [95% CI, 1.13–3.97]; P<0.05), which did not reach statistical significance after adjusted.

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an increasing trendno p-value reported

Similarly, the risk of HDP exhibited an increasing trend from F1 to F4, with F3 showing a moderate association (HDP: aRR, 5.86 [95% CI, 2.41–14.25]; P for trend< 0.001) and F4 showing a stronger association (HDP: aRR, 6.45 [95% CI, 1.78–23.33]; P for trend< 0.001).

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