Reply to the Letter to the Editor: "Revisiting Triglyceride-Glucose Index in HCM and HFpEF: Clarifying Confounders and Interpretative Limitations".

Anatol J Cardiol · 2026 · PMC13071558 · PMID 41524394

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did not reach statistical significanceno p-value reported

In diabetic patients, the point estimates for the TyG index also suggested a trend toward reduced risk for both all-cause mortality (HR: 0.92, 95% CI: 0.53-1.58, P = .755) and cardiovascular mortality (HR: 0.89, 95% CI: 0.45-1.78, P = .750), although these associations did not reach statistical significance, likely due to the small sample size of this subgroup (n = 137, 12.5% of the cohort).

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