Barely Significant
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High Expression of PAPP-A Predicts Poor Outcomes in Oestrogen Receptor-Positive Breast Cancer Patients.

Cancer Med · 2026 · PMC13072045 · PMID 41972358

1
hedged sentence
0.7130
closest p · 14.3× alpha
0.7130
boldest claim

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did not reach statistical significancep = 0.713not close (p > 0.1)
Analysis of an additional cohort of 172 ER+ cancers showed a similar trend with increased total PAPP‐A associated with worse survival, although this did not reach statistical significance (HR 5.759, 95% CI NA, p = 0.713) (Figure 3D ).

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