Notably, PBMCs from patients with progressive disease also showed a trend for higher proliferation, possibly reflecting intrinsic differences in proliferative potential and anergy ( Caligaris-Cappio, 2014 ; Haselager et al., 2023 ; ten Hacken et al., 2019 ).
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A 3D lymph node model for chronic lymphocytic leukaemia recapitulates microenvironmental features and drug response in vitro.
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