Non-Secreted Mature Decoy-Resistant IL-18-Armed Oncolytic Vaccinia Virus Elicits Potent Antitumor Effects in an Aggressive Murine Ovarian Cancer Model.

Cancers (Basel) · 2026 · PMC13072163 · PMID 41976287

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did not reach statistical significanceno p-value reported

Although the reduction in CD39 + CD103 + CD8 + PD-1 high T cells did not reach statistical significance relative to vvDD, this shift may suggest improved functional fitness of tumor-reactive CD39 + CD103 + CD8 + T cells following nsmDR-18 delivery.

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