Mesenchymal Stromal Cells Respond to SARS-CoV-2 Peptides and Exhibit Altered T-Cell Regulatory Capacity.

In response to T COVID , MSCs showed a trend to elevated levels of IL-6 ( Figure S3a , mean 23.337 ± SEM 24.725, n = 3), IL-1β ( Figure S3b , mean 27.877 ± SEM 25.697, n = 3) and tumor necrosis factor (TNF)-α ( Figure S3c , mean 5.365 ± SEM 4.581, n = 3) compared to coculture with T unstim (IL-6 mean 5.15 ± SEM 4.917, IL-1β mean 7.4 ± SEM 6.521, TNF-α mean 2.263 ± SEM 0.055) ( Figure S3a–c ).

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