Prognostic Impact of the Lung Immune Prognostic Index in Metastatic Non-Small Cell Lung Cancer Patients Treated with Nivolumab.

Although a numerical trend toward shorter PFS was observed with worsening LIPI categories in our cohort, this difference did not reach statistical significance.

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With respect to treatment response, objective response rates differed numerically across LIPI categories, with rates of 38.8%, 33.9%, and 20% observed in the good, intermediate, and poor LIPI groups, respectively; however, these differences did not reach statistical significance. Similar findings have been reported by Ruiz Bañobre and Zhi et al., who also did not observe a significant association between LIPI classification and objective response rates [ 13 , 14 ].

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