Semi-Automated Neuromelanin-Sensitive MRI Reveals Substantia Nigra Volume Reduction in Early Parkinson's Disease with Moderate Diagnostic Performance.

Diagnostics (Basel) · 2026 · PMC13073187 · PMID 41975757

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did not reach statistical significancep > 0.05actually significant

Neuromelanin Volume Measurements NM-MRI parameters showed trends toward reduced SN area and volume in PD patients [ 26 ] compared to controls, though these differences did not reach statistical significance ( p > 0.05) ( Table 4 ).

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