Intestinal Microfold Cells Play a Critical Role in the Uptake and Oral Tolerance Mediated by Lysophosphatidylserine-Containing Lipidic Nanoparticles.

Nanomaterials (Basel) · 2026 · PMC13074963 · PMID 41972628

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Interestingly, LysoPS-OVA treatment showed a trend of increased frequencies of Foxp3 + Tregs in the bone marrow of C57BL/6 mice, while their frequency was significantly reduced in RANKΔIEC mice ( Supplementary Figure S4C ).

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