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Phosphorothioate antisense oligonucleotide induced innate immune activation is attenuated by tryptophan oxidation products.

Nucleic Acids Res · 2026 · PMC13076217 · PMID 41978261

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showed a trendno p-value reported
In addition, 3HK showed a trend toward higher secretion, whereas 3-HAA, FAA, and AA were all increased compared with untreated controls and ASO 38.

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