Barely Significant
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Unraveling the molecular mechanisms of smoking-associated non-small cell lung cancer: a comprehensive analysis of genetic, therapeutic, and immunological.

J Thorac Dis · 2026 · PMC13077361 · PMID 41988285

1
hedged sentence
0.0900
closest p · 1.8× alpha
0.0900
boldest claim

The sentences

did not reach statistical significanceP=0.09so close (0.05 < p ≤ 0.1)
Although the differences in treatment efficacy did not reach statistical significance, a discernible trend was observed wherein current smokers exhibited a higher response rate to immunotherapy compared to reformed smokers and never smokers (P=0.09, Figure S1D ).

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