Alternative splicing-triggered mRNA decay informs splice-switching targets for neurodevelopmental disorders.

J Clin Invest · 2026 · PMC13078869 · PMID 41678398

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a clear trendno p-value reported

In Upf1 -KD, CHX-treated, and Upf2 conditional knockout samples, we observed a clear trend of increased PSI values for embryonic NMD_in events and decreased PSI values for NMD_ex events ( Supplemental Figure 4G ).

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