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Dual-trigger model of CD20 escape: NONO regulation and cryptic splicing induced by transcript overload in pediatric B-ALL.

Front Immunol · 2026 · PMC13079139 · PMID 41993182

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Hyperdiploid karyotypes (any form) were observed in 11 of 22 cases, of which 4 (36%) showed CD20 high expression; however, the association between hyperdiploidy and CD20 expression did not reach statistical significance.

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