Dose-dependent association between elevated resting IL-6 levels and severity of mental stress-induced myocardial perfusion defects.

Psychol Med · 2026 · PMC13079205 · PMID 41943927

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did not reach statistical significanceno p-value reported

Nevertheless, in the validation cohort of that research, they also observed numerically higher median IL-6 and hsCRP levels in MSIMI+ compared to MSIMI- patients, although these differences did not reach statistical significance.

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borderline significanceno p-value reported

Rank-transformed IL-6 showed a similar direction of association and reached either statistical significance or borderline significance, reflecting a consistent trend across modeling approaches.

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