Long-term clinical and radiological trajectories in ANO5-related myopathies highlight muscle MRI as a predictor of disease progression.

J Neurol · 2026 · PMC13079537 · PMID 41981189

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a decreasing trendno p-value reported

CK levels fluctuated during the follow-up, and 20% of patients showed a decreasing trend in CK values.

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did not reach statistical significanceno p-value reported

Regarding complementary tests, dystrophic features on muscle biopsy and myopathic changes on EMG tended to correlate with symptomatic phenotypes, although these associations did not reach statistical significance.

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