Meningeal macrophages regulate fibroblasts to influence meningeal lymphatic function following traumatic brain injury.

Compared with the PBS + TBI group, the CLO + TBI group showed a decrease in performance on the adhesive removal test at 5 and 7 days after TBI, indicating that macrophage depletion impairs sensory-motor functional recovery following TBI, whereas the cylinder test and foot fault test showed some differences but did not reach statistical significance.

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We found that PDGF-C treatment resulted in a highly significant concentration-dependent increase in VEGF-C levels (Figure 5 M-N).

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