Barely Significant
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The Effect of High-Density Lipoprotein on the Rheumatic Mitral Valve Calcification and Surgical Prognosis.

JACC Asia · 2026 · PMC13080751 · PMID 41201421

Europe PMCDOI
2
hedged sentences
0.0500
closest p · 1.0× alpha
0.0500
boldest claim

The sentences

did not reach statistical significanceP > 0.05actually significant
HDL levels were significantly negatively correlated with mitral valve calcification (HR: 0.09; 95% CI: 0.01-0.58; P = 0.012), while other variables (eg, age, BMI, diabetes) did not reach statistical significance ( P > 0.05).

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highly significantno p-value reported
The results suggest that HDL may be an independent protective factor for the degree of mitral valve calcification, remaining highly significant even after adjustment for potential confounding factors such as age and diabetes.

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.