Associations between tumor immune response and prognosis in node-negative breast cancer patients in the randomized DBCG HYPO trial.

BMC Cancer · 2026 · PMC13081644 · PMID 41826895

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High TILs (cut-off ≥ 30%) were observed in 18% of tumors and showed a trend toward improved outcomes, most pronounced in patients with estrogen receptor (ER)-negative tumors (hazard ratio (HR) 0.43, 95% CI (0.09–2.03)).

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