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Multiomics profiling and experiments in preclinical models revealed RAD51-IN-1 as a synergistic potentiator of anlotinib sensitivity.

Sci Adv · 2026 · PMC13082322 · PMID 41984951

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Other genes such as NOTCH1 , PRKD1 , TBX3 , and WNK2 showed higher mutation rates in the resistant group (each 50% versus 8.3%, P = 0.0833), although the differences did not reach statistical significance.

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