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Association between the serum uric acid-to-creatinine ratio index and the risk of preeclampsia in advanced maternal age pregnant women: a retrospective cohort study.

Front Cardiovasc Med · 2026 · PMC13082976 · PMID 42006615

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The overall association between the SUA/sCr index and preeclampsia was statistically significant ( P for overall < 0.001), while the test for nonlinearity did not reach statistical significance ( P for nonlinearity = 0.354), suggesting that the relationship was not strongly nonlinear across the full exposure range.To further investigate possible threshold effects, a two-piecewise linear regression model was applied ( Table 3 ).

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