Serum creatinine outperforms the creatinine to cystatin C ratio and creatinine muscle index as biomarkers in Chinese pediatric spinal muscular atrophy.

Front Hum Neurosci · 2026 · PMC13083190 · PMID 42003982

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.0500

boldest claim

The sentences

failed to reach significancep > 0.05actually significant

In contrast, RULM failed to reach significance at any timepoint (all p > 0.05) despite observable improvement trends.

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did not reach statistical significancep > 0.05actually significant

Revised Upper Limb Module (RULM) scores showed an initial improvement trend during the first 6–10 months; however, changes from baseline did not reach statistical significance at any timepoint (all p > 0.05).

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