A repeat expansion in GOLGA8A is a major risk factor for atypical frontotemporal lobar degeneration with ubiquitin-positive inclusions.

Nat Genet · 2026 · PMC13083237 · PMID 41820575

Europe PMC DOI

hedged sentence

0.0430

closest p · 0.9× alpha

0.0430

boldest claim

The sentences

nominally significantP = 0.043actually significant

Comparison of aFTLD-U cases with and without chr15q14 risk haplotypes We observed a nominally significant difference in age at death ( P = 0.043; Fig. 7a ) between aFTLD-U cases carrying haplotype A or B and those without association to chr15q14, with a subset of those without the haplotype showing an earlier age at death.

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