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Multiomics Biomarkers for Differential Diagnosis of Pleural Effusion: Integration of Proteomic Markers and Single-Cell Transcriptomics.

Hum Mutat · 2026 · PMC13084142 · PMID 42006152

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Fourth, integrative correlation analysis revealed that CEA levels showed inverse correlation with CD8+ T cell percentages (Spearman rho = −0.19, p < 0.001) and weak correlation with M2 macrophage proportions (rho = 0.06, p = 0.44) that did not reach statistical significance (Figure 4e ).

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