Barely Significant
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Reduction in Pigment Epithelial Detachment Thickness with Faricimab versus Aflibercept 2 mg during Head-to-Head Dosing in TENAYA/LUCERNE.

Ophthalmol Sci · 2026 · PMC13084404 · PMID 42005909

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nominally significantP < 0.05actually significant
In eyes with serous PED at baseline, faricimab resulted in a greater decrease in maximum PED thickness throughout head-to-head dosing compared with aflibercept ( Fig 1 B), with nominally significant differences (nominal P < 0.05) at weeks 4 and 12.

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