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Divergent behavioral strategies in Wistar and Wistar-Kyoto rats in a naturalistic task reveal mood disorder phenotypes.

iScience · 2026 · PMC13084746 · PMID 42006379

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Although back-angle differences did not reach statistical significance, our analyses suggest potential strain- and sex-dependent variation in posture that warrants further investigation, as the slowed movement and increased stretch-attend and stretch-approach posture suggest that the Kyoto females, in particular, engage in more risk assessment behaviors, a behavioral correlate of anxiety. 35 , 36 , 37 , 38 Discussion In this study, we compared the food hoarding and exploratory behavior of Wistar and Kyoto rats using a food hoarding task.

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