Carbonic anhydrase 9 as a circulating biomarker and therapeutic target in patients with hepatocellular carcinoma treated with atezolizumab plus bevacizumab.

J Immunother Cancer · 2026 · PMC13084789 · PMID 41956541

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a positive trendno p-value reported

did not reach statistical significanceno p-value reported

As an exploratory analysis, we examined the relationship between tumorous CA9 mRNA expression and circulating CA9 levels in 32 HCC specimens and observed a positive trend that did not reach statistical significance when assessed by Spearman’s rank correlation ( online supplemental figure 8 , online supplemental table 15 ).

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