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Topical NAMPT activation restores mitophagic flux to rescue diabetic keratopathy via the NAD⁺/PINK1 pathway.

Cell Commun Signal · 2026 · PMC13085529 · PMID 41803940

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It also upregulated the mitochondrial biogenesis markers TFAM and TOMM20, whereas the increase in NRF1 expression did not reach statistical significance (Fig. 4 G, J–L).

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