Prognostic value of the fibrosis-4 index for predicting in-hospital mortality in sepsis patients: evidence from MIMIC-IV and eICU databases.

Sci Rep · 2026 · PMC13087117 · PMID 41795025

Europe PMC DOI

hedged sentences

0.0510

closest p · 1.0× alpha

0.9900

boldest claim

The sentences

did not reach statistical significanceP = 0.051so close (0.05 < p ≤ 0.1)

However, the association did not reach statistical significance in the hepatitis (HR = 1.88, P = 0.051) and cirrhosis (HR = 1.6, P = 0.162) subgroups (Table 7 ).

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highly significantP > 0.99not close (p > 0.1)

Racial composition, however, showed a highly significant difference ( P > 0.99): the proportion of White patients was lower in the non-survivor group (57.77%) than in the survivor group (63.43%), whereas other racial groups were more prevalent among non-survivors.

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marginal significanceno p-value reported

Stratified Cox regression also confirmed that the high FIB-4 group (HR = 1.301, P < 0.0001) was a significant risk factor, while the low FIB-4 group (HR = 1.204, P = 0.0752) showed only marginal significance, with a log-likelihood ratio < 0.0001 (Table S8).

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