ApoE4 Drives Microglial Lipid Dysregulation in Alzheimer's Disease via Epigenetic Reprogramming of the Asxl1/LXRα-H3K4me3 Axis.

J Neuroinflammation · 2026 · PMC13088513 · PMID 41808104

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did not reach statistical significanceno p-value reported

Violin plot analysis indicated that Asxl1was expressed across all subclusters, showing a trend of decreased expression in activated states such as DAM and LDAM, although this did not reach statistical significance (Fig. 3 D).

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