Studies of renal clear cell, hepatocellular and colorectal carcinomas revealed a higher frequency of 1q21-q23 gains in metastatic tumours [ 10 , 11 ], and gains of 1q21-q25 showed a trend toward short overall survival in high-grade osteosarcomas and neuroblastomas [ 12 , 13 ].
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Mapping and characterization of the amplicon near APOA2 in 1q23 in human sarcomas by FISH and array CGH.
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