Barely Significant
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C-reactive protein as a predicting factor for difficult laparoscopic cholecystectomy or its conversion to open cholecystectomy in acute calculous cholecystitis: an observational study.

BMC Surg · 2026 · PMC13088770 · PMID 41803849

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Despite a higher conversion rate to open surgery among males (16.7%) compared to females (6.0%), and a higher incidence of difficult laparoscopic cases in females (28.6%), these differences did not reach statistical significance (Table 1 ).

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