Gut microbiome and metabolome signatures in calcium oxalate stone recurrence: a multi-omics study.

Key enzymes related to SCFA production, such as butyrate kinase, acetyl-CoA acetyltransferase, acyl-CoA synthetase and β-ketoacyl-ACP synthase, also showed descriptive differences in abundance between FS and RS groups—with lower levels in the FS group and relatively higher levels in the RS group—but these changes did not reach statistical significance (all FDR-adjusted P > 0.05).

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