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A meta-analysis of sexual orientation inequities in substance use among youth.

Addiction · 2026 · PMC13088934 · PMID 41437853

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The analysis of sexual orientation measurement types revealed that among lesbian/gay participants, identity‐based measures showed 45% higher odds (OR = 1.45; 95% CI = 1.30–1.62, I 2 = 94.53, participants = 2 386 871, studies = 81) and attraction‐based measures showed 68% higher odds (OR = 1.68; 95% CI = 1.14–2.49, I 2 = 82.17, participants = 43 440, studies = 7) of substance use compared to their heterosexual counterparts, while behavior‐based measures did not reach statistical significance (OR = 1.26; 95% CI = 0.89–1.78, I 2 = 87.03, participants = 523 110, studies = 10).

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