A Novel Long Noncoding RNA-LNC000133 Associated With Steroid-Induced Osteonecrosis of the Femoral Head Promotes Osteoblast Differentiation Through Bone Marrow Mesenchymal Stem Cells-Derived Exosomes Pathway: A Bioinformatics Validation and Detailed Mechanistic Study.

J Cell Mol Med · 2026 · PMC13090172 · PMID 41998815

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Additionally, ALP staining and activity assays revealed significantly higher ALP activity in the up‐LNC000133‐Exo group compared with the control group, while the sh‐LNC000133‐Exo group showed a trend toward inhibited ALP activity ( p < 0.05) (Figure 5C,D ).

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