Developmental Alterations in the Diffusion Tensor Imaging Analysis Along the Perivascular Space Index Suggest Possible Glymphatic-Related Mechanisms Underlying Excitation/Inhibition Imbalance and Psychosis Vulnerability in 22q11.2 Deletion Syndrome.

Biol Psychiatry Glob Open Sci · 2026 · PMC13091000 · PMID 42005288

Europe PMC DOI

hedged sentence

0.2530

closest p · 5.1× alpha

0.2530

boldest claim

The sentences

did not reach statistical significancep = .253not close (p > 0.1)

The left hemisphere showed a slightly reduced ALPS index in the 22q11DS group, but the difference did not reach statistical significance (β = −0.03; 95% CI, −0.08 to 0.02; p = .253) ( Figure 1B and Table S4B ).

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