The differential tests did not reach statistical significance after correction, meaning that the observed asymmetry between disorders at the pathway level should be regarded as exploratory rather than confirmatory.
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Synaptic Plasticity Fragility Underlies a Microglial Pruning Continuum in Major Depressive Disorder and Amyotrophic Lateral Sclerosis.
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The sentences
The two negative control sets performed as expected: housekeeping genes returned a p-value of 0.098, and monoaminergic pathways came in at 0.71, with neither anywhere close to significance.