Further exploring the specific effects of Fmr1 and IP3R2 genotype on the nearly significant group differences with a two-way ANOVA of seizure score, we found that, consistent with our previous Fmr1 KO cohort and many previously published studies, there was a main effect of Fmr1 genotype on seizure score ( F (1, 72) = 7.35, p = .008; Fig. 7B ).
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Contribution of astrocytic calcium signaling to auditory hypersensitivity in a mouse model of fragile X syndrome.
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