Dapagliflozin: A Role for Heart Failure Treatment in Dialysis?

Kidney Int Rep · 2026 · PMC13091423 · PMID 42006223

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narrowly missed statistical significanceno p-value reported

For example, the change in NT-proBNP narrowly missed statistical significance and was in the direction of benefit, consistent with other trials of SGLT2i in nondialysis populations.

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did not reach statistical significanceno p-value reported

Higher (improved) KCCQ scores were also noted for dapagliflozin-treated individuals versus standard of care, but did not reach statistical significance; there was no meaningful effect on the 6-minute walk test distance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.