Adverse Drug Reactions to Antihypertensive Therapy: A Prospective Evaluation of Causality and Severity Using the World Health Organization-Uppsala Monitoring Centre (WHO-UMC) and Hartwig-Siegel Scales.

Cureus · 2026 · PMC13091690 · PMID 42005142

Europe PMC DOI

hedged sentence

0.8900

closest p · 17.8× alpha

0.8900

boldest claim

The sentences

did not reach statistical significancep = 0.89not close (p > 0.1)

Similarly, although patients receiving combination antihypertensive therapy demonstrated slightly higher odds of developing ADRs compared with those receiving monotherapy (OR = 1.06, 95% CI = 0.48-2.33), this association did not reach statistical significance (p = 0.89).

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