Structured higher protein meal replacement plans for weight loss and metabolic health: A qualitative narrative evidence review of Medifast interventions.

Obes Pillars · 2026 · PMC13091830 · PMID 42011406

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did not reach statistical significanceno p-value reported

All 4 RCTs reported statistically significant between-group reductions, while the open-label pilot trial (n = 20) did not reach statistical significance for between-group differences.

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