Capecitabine versus Paclitaxel After CDK4/6 Inhibitor Progression in Hormone Receptor-Positive, HER2-Negative Metastatic Breast Cancer: A Real-World Study.

Breast Cancer (Dove Med Press) · 2026 · PMC13092254 · PMID 42011243

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did not reach statistical significancep = 0.052so close (0.05 < p ≤ 0.1)

a trend towards significanceno p-value reported

In multivariate analysis, tumor grade emerged as the only independent predictor of OS (HR 1.82, 95% CI 1.10–3.01; p = 0.018), while endocrine sensitivity showed a trend towards significance but did not reach statistical significance (HR 1.62, 95% CI 0.99–2.63; p = 0.052).

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