Systematic Review, Meta-analysis, and Trial Sequential Analysis of Randomised Controlled Trials Comparing Balloon Expandable with Self Expanding Stents for the Treatment of Iliac Artery Occlusive Disease.

Similarly for MAVE, the obtained information size was lower than the required information size, and the cumulative z score did not reach statistical significance by crossing either the conventional or O'Brian–Fleming boundaries, meaning that the results of the meta-analysis were inconclusive and further trials are required to demonstrate the presence or absence of a significant effect ( Fig. 4 B).

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