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Midkine Overexpression Promotes Functional Recovery After Spinal Cord Injury by Enhancing Microglial Efferocytosis Via LRP-1.

CNS Neurosci Ther · 2026 · PMC13093358 · PMID 41854297

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In addition, we observed that during the acute phase following SCI, rats overexpressing MDK exhibited significant behavioral improvement, although the MDK protein level, while showing an upward trend compared with the natural injury group, did not reach statistical significance.

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