<i>Arachis hypogaea</i> L. Root Extract Mitigates Testosterone Propionate-Induced Benign Prostatic Hyperplasia in ICR Mice by Suppressing Inflammation, Androgen Receptors, and Dihydrotestosterone.

Faecalibacterium and Roseburia exhibited modest links to T/E 2 ratio, hinting at potential microbial contributions to estrogenic modulation; however, these associations did not reach statistical significance after BH‐FDR correction and thus warrant further validation.

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It's worth noting that Firmicutes exhibited a decreasing tendency, while Bacteroidetes displayed an increasing trend when the NC group was compared to the blank group, AHRE MD, and AHRE HD groups (Figure 4A ). 3.7 AHRE Modulates Gut Microbiota to Prevent BPH By analyzing the taxonomic distribution, significant distinctions in the flora at the genus, family, and phylum levels were observed when comparing the PC group with the blank and AHRE treated groups, particularly the AHRE MD and HD groups (Figure 4 ).

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While fewer comparisons reached strong significance compared to PCA, dose‐dependent contrasts involving higher AHRE doses remained highly significant with elevated pseudo‐ F values (e.g., Blank vs.

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