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Multiple Adverse Outcomes Associated with Risperidone in People with Dementia: An Individual Participant Data Meta-Analysis.

CNS Drugs · 2026 · PMC13095927 · PMID 41776136

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The presence of psychosis at baseline was associated with a lower risk of MACE in the risperidone group (HR 0.42; 95% CI 0.21–0.82; p = 0.012) and in the placebo group (HR 0.55; 95% CI 0.18–1.63; p = 0.278), although the latter did not reach statistical significance.

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