A comprehensive analysis of humanized mouse models for the study of cancer immunotherapies.

Front Immunol · 2026 · PMC13096022 · PMID 42023233

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did not reach statistical significanceno p-value reported

Four PDX models (LCF13, LCF15, LCF16, and LCF25) showed no detectable response to anti-PD1 therapy, whereas the remaining four models (LCF17, LCF22, LCF29, and LCF26) displayed only mild trends toward response that did not reach statistical significance ( Figure 5B ).

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